Periodic fevers with aphthous stomatitis, pharyngitis, and adenitis (PFAPA).

@article{Vigo2012PeriodicFW,
  title={Periodic fevers with aphthous stomatitis, pharyngitis, and adenitis (PFAPA).},
  author={Giulia Vigo and F Zulian},
  journal={Autoimmunity reviews},
  year={2012},
  volume={12 1},
  pages={52-5}
}
PFAPA syndrome (acronym of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) is the most common cause of periodic fever in childhood. Nowadays, it is considered part of the wide family of the autoinflammatory diseases, but a genetic or molecular marker hasn't been identified yet, therefore, its etiology is still unknown. Diagnosis is essentially based on clinical criteria but, especially in younger children, it is sometimes difficult to differentiate it from other… CONTINUE READING
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