Periodic fever, aphthous stomatitis, pharyngitis, adenitis: a clinical review of a new syndrome.

@article{Feder2000PeriodicFA,
  title={Periodic fever, aphthous stomatitis, pharyngitis, adenitis: a clinical review of a new syndrome.},
  author={Henry M. Feder},
  journal={Current opinion in pediatrics},
  year={2000},
  volume={12 3},
  pages={253-6}
}
Periodic fevers (fevers that occur predictably at fixed intervals) are unusual in infants and children. The classic periodic fever syndrome is cyclic neutropenia (neutropenia followed by infections and fever that recur every 21 days). A new periodic fever syndrome PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) has been characterized over the past decade. PFAPA is defined clinically, because specific laboratory abnormalities have not been found. The clinical… CONTINUE READING

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Mutations in the gene encoding mevalonate kinase cause hyperIgD and periodic fever syndrome

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