Periodic fatigue symptoms due to desynchronization in a patient with non‐24‐h sleep–wake syndrome

  title={Periodic fatigue symptoms due to desynchronization in a patient with non‐24‐h sleep–wake syndrome},
  author={Kayo Shibui and Makoto Uchiyama and Hisayuki Iwama and Shigeru Ozaki and K. Takahashi and Masako Okawa},
  journal={Psychiatry and Clinical Neurosciences},
A 43‐year‐old man complaining of recurrent fatigue symptoms and sleep disorders occurring periodically every 4 weeks was studied. Using a wrist worn actigraphy and an ambulatory rectal temperature monitoring apparatus, his sleep–wake cycle and rectal temperature were measured continuously for 4 months, while diagnostic evaluation and therapeutic interventions were conducted. It was found that after he gave up an attempt to keep to a 24‐h‐day, a free‐running sleep–wake pattern appeared but his… 
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