Periodic apnea, exercise hypoventilation, and hypothalamic dysfunction.

@article{Moskowitz1976PeriodicAE,
  title={Periodic apnea, exercise hypoventilation, and hypothalamic dysfunction.},
  author={Mark A. Moskowitz and Joseph N. Fisher and M D Simpser and Denise J Strieder},
  journal={Annals of internal medicine},
  year={1976},
  volume={84 2},
  pages={171-3}
}
Periodic apnea and exercise hypoventilation were observed in a 14-year-old boy. Hyperphagia, obesity, serum hyperosmolality without diabetes insipidus or appropriate thirst, and retardation of growth and sexual development indicated a hypothalamic disorder. Neurologic evaluation was normal except for electroencephalographic changes induced by apnea. Pulmonary function tests, resting arterial blood gases in the wakeful state, and ventilatory response to inhaled CO2 were also normal. Acute… CONTINUE READING