Perineural tumor spread of bladder cancer causing lumbosacral plexopathy: an anatomic explanation

@article{Aghion2014PerineuralTS,
  title={Perineural tumor spread of bladder cancer causing lumbosacral plexopathy: an anatomic explanation},
  author={Daniel M. Aghion and Stepan Capek and Benjamin Matthew Howe and Jaroslaw T. Hepel and Sundaresan Sambandam and Adeotounbo A. Oyelese and Robert J Spinner},
  journal={Acta Neurochirurgica},
  year={2014},
  volume={156},
  pages={2331-2336}
}
We present two cases of biopsy-proven neoplastic lumbosacral plexopathy from perineural spread of bladder cancer: one patient presented with predominantly sciatic nerve involvement and the second predominantly with obturator nerve involvement. These two patterns of perineural spread from bladder cancer were supported by imaging in our cases and solidified by review of the literature. Based on the innervation of the bladder, we provide an anatomic explanation for this observation. To our best… CONTINUE READING
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