Perineural invasion of the lower alveolar nerve by oral cancer: a follow-up study of 12 cases.

@article{Zupi1998PerineuralIO,
  title={Perineural invasion of the lower alveolar nerve by oral cancer: a follow-up study of 12 cases.},
  author={Aldo Zupi and Giuseppe Michele Mangone and Pasquale Piombino and Leonardo L Califano},
  journal={Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery},
  year={1998},
  volume={26 5},
  pages={
          318-21
        }
}
Twelve previously untreated cases of oral cancer with perineural infiltration were studied retrospectively. Age, sex, site, clinical stage and outcome were evaluated. Management of the neoplasm in each case involved surgical removal and six patients required adjuvant radiotherapy. The most frequent site was the lip. At the time of diagnosis, five patients had sensory complaints and palpable lymphadenopathy was observed in three patients. The 5-year crude survival rate was 16.7%. In the cases… CONTINUE READING
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