Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma.

@article{Shen2014PerineuralIA,
  title={Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma.},
  author={W Shen and Yiping Wang and Julia Yu-Fong Chang and Shang-Yang Yu and H. Chen and C. -H. Chiang},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2014},
  volume={43 4},
  pages={258-64}
}
BACKGROUND Perineural invasion (PNI) and nerve growth factor (NGF) expression are found to be significantly associated with the progression and/or prognosis of several human cancers. METHODS Immunohistochemical staining for S-100 and NGF proteins was performed to assess the PNI and NGF expression level in 116 oral tongue squamous cell carcinoma (OTSCC… CONTINUE READING