Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension.

@article{Neglia2011PerindoprilAI,
  title={Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension.},
  author={Danilo Neglia and Enza Fommei and Anabel Varela-Carver and Massimiliano Mancini and Sergio Ghione and Massimo Lombardi and Patrizia Costa Pisani and Howard Parker and Giulia d'Amati and Luigi Donato and Paolo G. Camici},
  journal={Journal of hypertension},
  year={2011},
  volume={29 2},
  pages={364-72}
}
OBJECTIVES Patients and animal models of arterial hypertension are characterized by structural and functional abnormalities of the coronary microcirculation. Using a translational approach, we ascertained whether antihypertensive treatment can reverse microvascular remodelling and improve myocardial perfusion. METHODS In 20 hypertensive patients with left ventricular hypertrophy, blood pressure, left ventricular mass index and myocardial blood flow were measured at baseline and after 6 months… CONTINUE READING
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