Perindopril Attenuates Lipopolysaccharide-Induced Amyloidogenesis and Memory Impairment by Suppression of Oxidative Stress and RAGE Activation.

@article{Goel2016PerindoprilAL,
  title={Perindopril Attenuates Lipopolysaccharide-Induced Amyloidogenesis and Memory Impairment by Suppression of Oxidative Stress and RAGE Activation.},
  author={Ruby Goel and Shahnawaz Ali Bhat and Kashif Hanif and Chandishwar Nath and Rakesh Kumar Shukla},
  journal={ACS chemical neuroscience},
  year={2016},
  volume={7 2},
  pages={206-17}
}
Clinical and preclinical studies account hypertension as a risk factor for dementia. We reported earlier that angiotensin-converting enzyme (ACE) inhibition attenuated the increased vulnerability to neurodegeneration in hypertension and prevented lipopolysaccharide (LPS)-induced memory impairment in normotensive wistar rats (NWRs) and spontaneously… CONTINUE READING