Perinatal nicotine exposure impairs ability of newborn rats to autoresuscitate from apnea during hypoxia.

@article{Fewell1998PerinatalNE,
  title={Perinatal nicotine exposure impairs ability of newborn rats to autoresuscitate from apnea during hypoxia.},
  author={James E. Fewell and Francine G Smith},
  journal={Journal of applied physiology},
  year={1998},
  volume={85 6},
  pages={2066-74}
}
Failure to autoresuscitate by hypoxic gasping during prolonged sleep apnea has been suggested to play a role in sudden infant death. Furthermore, maternal smoking has been repeatedly shown to be a risk factor for sudden infant death. The present experiments were carried out on newborn rat pups to investigate the influence of perinatal exposure to nicotine (the primary pharmacological and addictive agent in tobacco) on their time to last gasp during a single hypoxic exposure and on their ability… CONTINUE READING

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