Perinatal hypothyroidism effects on neuromotor competence, novelty-directed exploratory and anxiety-related behaviour and learning in rats.

@article{Darbra2003PerinatalHE,
  title={Perinatal hypothyroidism effects on neuromotor competence, novelty-directed exploratory and anxiety-related behaviour and learning in rats.},
  author={S{\`o}nia Darbra and A. Garau and Ferran Balada and Josefina Sala and Maria Assumpci{\'o} Mart{\'i}-Carbonell},
  journal={Behavioural brain research},
  year={2003},
  volume={143 2},
  pages={209-15}
}
Thyroid hormone is essential for proper development of the mammalian CNS. Previous studies have documented a decrease in the ability of neonatal hypothyroid animals to learn and to habituate to maze tests and an increase in spontaneous activity. However, there is little information about the effects of perinatal (i.e. perinatal and postnatal) hypothyroidism on behaviour. The aim of the present work was to investigate the longitudinal effects of perinatal hypothyroidism on certain aspects of the… CONTINUE READING

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