Perinatal fluoxetine effects on social play, the HPA system, and hippocampal plasticity in pre-adolescent male and female rats: Interactions with pre-gestational maternal stress.

@article{Gemmel2017PerinatalFE,
  title={Perinatal fluoxetine effects on social play, the HPA system, and hippocampal plasticity in pre-adolescent male and female rats: Interactions with pre-gestational maternal stress.},
  author={Mary Gemmel and Mariah Hazlett and Eszter B{\"o}gi and Sonsoles de Lacalle and Lesley A Hill and N Kokras and Geoffrey L. Hammond and Christina Dalla and Thierry D. Charlier and Jodi Pawluski},
  journal={Psychoneuroendocrinology},
  year={2017},
  volume={84},
  pages={159-171}
}
Selective serotonin reuptake inhibitor medications (SSRIs) are the first lines of treatment for maternal affective disorders, and are prescribed to up to 10% of pregnant women. Concern has been raised about how perinatal exposure to these medications affect offspring neurobehavioral outcomes, particularly those related to social interactions, as recent research has reported conflicting results related to autism spectrum disorder (ASD) risk in children prenatally exposed to SSRIs. Therefore, the… CONTINUE READING
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