Perinatal exposure to low-dose bisphenol A affects the neuroendocrine stress response in rats.

@article{Panagiotidou2014PerinatalET,
  title={Perinatal exposure to low-dose bisphenol A affects the neuroendocrine stress response in rats.},
  author={Emily Panagiotidou and Sophia Zerva and Dimitra J. Mitsiou and Michael N Alexis and Efthymia Kitraki},
  journal={The Journal of endocrinology},
  year={2014},
  volume={220 3},
  pages={
          207-18
        }
}
Bisphenol A (BPA) is an estrogen-mimicking endocrine disruptor. Early-life exposures to low doses of BPA exert long-lasting effects on animals' reproductive and brain physiology. However, little is known about the effects of BPA on the stress-response system. Given the interaction of sex and stress hormones, we examined the effect of a low perinatal BPA exposure on the function of the hypothalamic-pituitary-adrenal (HPA) axis at rest and upon application of acute stress. Throughout pregnancy… 

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