Perinatal bisphenol A affects the behavior and SRC-1 expression of male pups but does not influence on the thyroid hormone receptors and its responsive gene.

@article{Xu2007PerinatalBA,
  title={Perinatal bisphenol A affects the behavior and SRC-1 expression of male pups but does not influence on the thyroid hormone receptors and its responsive gene.},
  author={Xundi Xu and Yanli Liu and Miyuki Sadamatsu and Souichi Tsutsumi and Marie Akaike and Hirokage Ushijima and Nobumasa Kato},
  journal={Neuroscience research},
  year={2007},
  volume={58 2},
  pages={149-55}
}
Bisphenol A (BPA) has been shown to interfere with thyroid hormone receptors (THRs) and to influence the expression of THR-responsive elements in vivo and in vitro, while some studies reported hyperactivity induced by BPA treatment. In the present study, our purpose was to investigate the effect of BPA exposure on behavioral alteration and its mechanism of action, especially focusing on the thyroid hormone pathway. Significant sexual difference on behaviors was observed in perinatal BPA… CONTINUE READING