Perinatal asphyxia induces neurogenesis in hippocampus: an organotypic culture study

@article{Morales2007PerinatalAI,
  title={Perinatal asphyxia induces neurogenesis in hippocampus: an organotypic culture study},
  author={Paola Morales and P. Huaiquin and Diego A. Bustamante and Jenny Fiedler and Mario Herrera-Marschitz},
  journal={Neurotoxicity Research},
  year={2007},
  volume={12},
  pages={81-84}
}
There is clinical and experimental evidence indicating that neurocircuitries of the hippocampus are vulnerable to hypoxia/ischemia occurring at birth, inducing, upon re-oxygenation/re-circulation, delayed neuronal death, but also compensatory mechanisms, including neurogenesis. In the present report, perinatal asphyxia was induced by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath at 37°C for 20 min. Some pups were delivered immediately after the… CONTINUE READING
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