Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection

@inproceedings{Derscheid2012PerinatalLM,
  title={Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection},
  author={Rachel J. Derscheid and Mark R Ackermann},
  booktitle={Viruses},
  year={2012}
}
Respiratory syncytial virus (RSV) is the most frequent cause of bronchiolitis in infants and children worldwide. Many animal models are used to study RSV, but most studies investigate disease in adult animals which does not address the unique physiology and immunology that makes infants more susceptible. The perinatal (preterm and term) lamb is a useful model of infant RSV disease as lambs have similar pulmonary structure including airway branching, Clara and type II cells, submucosal glands… CONTINUE READING
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