Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase.

@article{Moore2005PerilipinTA,
  title={Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase.},
  author={Hsiao-Ping H Moore and Robert B Silver and Emilio P. Mottillo and David A Bernlohr and James G. Granneman},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 52},
  pages={43109-20}
}
Adipocytes serve as the principal energy reservoir of the body; however, the subcellular organization of the machinery regulating lipid trafficking and metabolism is poorly understood. Mobilization of stored triglyceride is thought be controlled by interactions among intracellular lipases and proteins that coat lipid storage droplets. A major limitation of previous studies of hormone-mediated lipolysis, however, is the use of cultured model adipocytes whose three-dimensional architectures do… CONTINUE READING

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