Perikaryal and synaptic localization of alpha 2A-adrenergic receptor-like immunoreactivity.

@article{Aoki1994PerikaryalAS,
  title={Perikaryal and synaptic localization of alpha 2A-adrenergic receptor-like immunoreactivity.},
  author={Chiye J Aoki and Cheer Germ Go and C Venkatesan and Hitoshi Kurose},
  journal={Brain research},
  year={1994},
  volume={650 2},
  pages={181-204}
}
Through molecular cloning, the existence of three distinct subtypes of alpha 2-adrenergic receptors (alpha 2AR)--A, B and C--has been established and are referred to as alpha 2A AR, alpha 2B AR and alpha 2CAR. Due to limitations in pharmacological tools, it has been difficult to ascribe the role of each subtype to the central functions of alpha 2AR. In situ hybridization studies have provided valuable information regarding their distribution within brain. However, little is known about their… CONTINUE READING
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