Periinfarct depolarizations.

  title={Periinfarct depolarizations.},
  author={K. A. Hossmann},
  journal={Cerebrovascular and brain metabolism reviews},
  volume={8 3},
  • K. A. Hossmann
  • Published 1996 in Cerebrovascular and brain metabolism reviews
In the surroundings of focal ischemic lesions, repetitive spreading depression (SD)-like depolarizations occur. These depolarizations are triggered by the anoxic release of potassium and excitatory amino acids from the infarct core, and they are propagated over the whole hemisphere at a speed of approximately 3 mm/min. The associated fluid shifts can be detected by diffusion-weighted magnetic resonance imaging (MRI) and correlate with an aggravation of the metabolic disturbance. In the… CONTINUE READING


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