Perifornical orexinergic neurons modulate REM sleep by influencing locus coeruleus neurons in rats

@article{Choudhary2014PerifornicalON,
  title={Perifornical orexinergic neurons modulate REM sleep by influencing locus coeruleus neurons in rats},
  author={Rishabh Charan Choudhary and M. A. Khanday and Arojit Mitra and B. N. Mallick},
  journal={Neuroscience},
  year={2014},
  volume={279},
  pages={33-43}
}
Activation of the orexin (OX)-ergic neurons in the perifornical (PeF) area has been reported to induce waking and reduce rapid eye movement sleep (REMS). The activities of OX-ergic neurons are maximum during active waking and they progressively reduce during non-REMS (NREMS) and REMS. Apparently, the locus coeruleus (LC) neurons also behave in a comparable manner as that of the OX-ergic neurons particularly in relation to waking and REMS. Further, as PeF OX-ergic neurons send dense projections… CONTINUE READING
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