Periconceptional vitamin useand leukemia risk in children with Down syndrome: a Children's Oncology Group study.

@article{Ross2005PericonceptionalVU,
  title={Periconceptional vitamin useand leukemia risk in children with Down syndrome: a Children's Oncology Group study.},
  author={Julie A. Ross and Cindy K. Blair and Andrew F. Olshan and Leslie L. Robison and Franklin O. Smith and Nyla A. Heerema and Michelle A. Roesler},
  journal={Cancer},
  year={2005},
  volume={104 2},
  pages={405-10}
}
BACKGROUND Periconceptional vitamin supplementation reduces the risk of neural tube defects, and possibly may reduce the risk of certain childhood malignancies, including acute lymphoblastic leukemia (ALL). Because children with Down syndrome (DS) experience a 20-fold higher risk of leukemia than the general population, the authors evaluated whether periconceptional vitamin supplementation reduced the risk of leukemia in children with DS. METHODS From 1997 to 2002, 158 children ages birth-18… CONTINUE READING
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