Pericentric inversion of chromosome 9 in prenatal diagnosis and infertility.

  title={Pericentric inversion of chromosome 9 in prenatal diagnosis and infertility.},
  author={Shigeki Uehara and Yasuhiro Akai and Yoichi Takeyama and Toshifumi Takabayashi and Kunihiro Okamura and Akira Yajima},
  journal={The Tohoku journal of experimental medicine},
  volume={166 4},
In order to evaluate the relation between pericentric inversion of chromosome 9 (inv(9)) and clinical problems, the characteristics of inv(9) were investigated on the basis of chromosomal analyses of fetuses and infertile couples. The incidence of such inversion in fetuses with parents having an offspring who suffered from various clinical problems was significantly higher than the basic incidence obtained in fetuses karyotyped by reason of advanced maternal age. In the chromosomal examination… CONTINUE READING