Peri-implant defect regeneration in the diabetic pig: A preclinical study.

  title={Peri-implant defect regeneration in the diabetic pig: A preclinical study.},
  author={Cornelius von Wilmowsky and Karl Andreas Schlegel and Christoph A Baran and Emeka Nkenke and Friedrich Wilhelm Neukam and Tobias Moest},
  journal={Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery},
  volume={44 7},
OBJECTIVES The study aims to establish a peri-implant dehiscence-type bone defect in a diabetic animal model of human bone repair and to quantify the influence of diabetes on peri-implant bone regeneration. MATERIAL AND METHODS Experimental diabetes was induced in three domestic pigs by streptozotocin. Three animals served as healthy controls. After 12 months four standardized peri-implant dehiscence bone defects were surgically created in the ramus mandibulae. The animals were sacrificed… CONTINUE READING