Perfusion parameters derived from bolus-tracking perfusion imaging are immune to tracer recirculation.

PURPOSE To investigate the impact of tracer recirculation on estimates of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). MATERIALS AND METHODS The theoretical model used to derive CBF, CBV, and MTT was examined. CBF and CBV estimates with and without tracer recirculation were compared in computer simulations to… CONTINUE READING