Perfusion of the interventricular septum during ventilation with positive end-expiratory pressure.

OBJECTIVE To determine whether regional hypoperfusion of the interventricular septum occurs during ventilation with positive end-expiratory pressure. DESIGN Animal study. ANIMALS Anesthetized, closed chest dogs (n = 8). INTERVENTIONS Induction of experimental adult respiratory distress syndrome (ARDS) and then ventilation with 10, 15, and 20 cm H2O of… CONTINUE READING