Performance of two new, automated chemiluminescence assay panels for anticardiolipin and anti-beta2-glycoprotein I antibodies in the laboratory diagnosis of the antiphospholipid syndrome.

@article{Hoecke2012PerformanceOT,
  title={Performance of two new, automated chemiluminescence assay panels for anticardiolipin and anti-beta2-glycoprotein I antibodies in the laboratory diagnosis of the antiphospholipid syndrome.},
  author={Frederik Van Hoecke and Lies Persijn and A S Decavele and Katrien M J Devreese},
  journal={International journal of laboratory hematology},
  year={2012},
  volume={34 6},
  pages={630-40}
}
INTRODUCTION Anticardiolipin (aCL) and anti-β2-glycoprotein I (aβ2GPI) antibodies are two of the three laboratory criteria for antiphospholipid syndrome (APS). All assays for antiphospholipid antibodies (aPL), coagulation assays as well as ELISAs, show methodological shortcomings, which makes the search for better assays everlasting. The purpose of this study was to investigate the diagnostic performance of two new, fully automated systems (Zenit RA and HemosIL Acustar) applying… CONTINUE READING
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