Performance of plasma free metanephrines measured by liquid chromatography-tandem mass spectrometry in the diagnosis of pheochromocytoma.

@article{Peaston2010PerformanceOP,
  title={Performance of plasma free metanephrines measured by liquid chromatography-tandem mass spectrometry in the diagnosis of pheochromocytoma.},
  author={Robert T Peaston and Kendon S Graham and Erin W. Chambers and Jan C van der Molen and Stephen Ball},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2010},
  volume={411 7-8},
  pages={546-52}
}
BACKGROUND Plasma free metanephrines have proved a highly sensitive biochemical test for the diagnosis of pheochromocytoma. We have developed and validated a simple, LC-MS/MS method to determine plasma metanephrines and compared the diagnostic efficacy of the method with an enzyme immunoassay procedure in 151 patients, 38 with histologically confirmed… CONTINUE READING