Performance of oxygen delivery devices when the breathing pattern of respiratory failure is simulated *

  title={Performance of oxygen delivery devices when the breathing pattern of respiratory failure is simulated *},
  author={Marcus Sim and P. Dean and John Kinsella and Roland Black and Rick Carter and Michael Hughes},
Oxygen is the commonest drug prescribed in hospitals. The inhaled concentration is altered by the administered oxygen flow rate, the characteristics of the delivery device and the patient’s respiratory pattern. Using healthy volunteers we measured the inspired oxygen concentration achieved with different devices both at rest and when the breathing pattern of respiratory failure was simulated by binding the subjects' chests until the forced expiratory volume in 1 s was reduced by > 50% and the… 
High Flow Nasal Oxygen Therapy: From Physiology to Clinic
Studies show that HFNO treatment improves physiological parameters when compared to conventional oxygen systems, and patient comfort is better in HFNO when compared with standard oxygen therapy and noninvasive mechanical ventilation (NIMV).
The efficacy of an oxygen mask with reservoir bag in patients with respiratory failure.
fixing an OMR very tightly to the face is mandatory for its effective use, and it should be kept in mind that there are limitations to the efficacy of OMR, even when they are used with such careful management.
Impact of Oxygen Concentration Delivered via Nasal Cannula on Different Lung Conditions: A Bench Study
The data suggest that the actual FiO2 is never as high in spontaneously breathing patients as that estimated, and VT and oxygen flow rate had a substantial impact on theFiO2.
Delivery of helium–oxygen mixture during spontaneous breathing: evaluation of three high-concentration face masks
The Hi-Ox80 mask minimized room air contamination and much more frequently achieved a pharyngeal He concentration higher than 50% in the airways.
Sequential Application of Oxygen Therapy Via High-Flow Nasal Cannula and Noninvasive Ventilation in Acute Respiratory Failure: An Observational Pilot Study
HFNC was better tolerated than NIV and allowed for significant improvement in oxygenation and tachypnea compared with standard oxygen therapy in subjects with AHRF, a large majority of whom had ARDS.
Nasal high–flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV)
In hypoxic respiratory failure HFNC offers a good balance between oxygenation and comfort compared to NIV and Venturi mask and seems to be well tolerated by patients.
High-flow nasal cannula oxygen therapy as an emerging option for respiratory failure: the present and the future
High-flow nasal cannula (HFNC) is an emerging technique, designed to provide oxygen at high flows with an optimal degree of heat and humidification, which is well tolerated and easy to use in all clinical settings.
High-Flow Nasal Cannula Therapy for Acute Hypoxemic Respiratory Failure in Adults: A Retrospective Analysis.
HFNC therapy showed a good compliance and the improvement of the physiologic parameters in an adult population, and the failure to improve oxygenation within 24 hours was a useful predictor of intubation.
High-Flow Nasal Cannula Therapy in Adults
High-flow nasal cannula (HFNC) oxygen therapy has been studied in adults with acute hypoxemic respiratory failure, patients with chronic obstructive pulmonary disease and heart failure, and for preoxygenation before intubation, as well as postextubation to avoid or treat respiratory failure in high-risk groups.


Performance of six types of oxygen delivery devices at varying respiratory rates *
A model is constructed using a resuscitation manikin, a ventilator and a set of bellows to simulate ventilation and shows that high flow systems show no failure of performance at increased respiratory rates.
Evaluation of five oxygen delivery devices in spontaneously breathing subjects by oxygraphy
Oxygen supply systems may be divided into constant and variable performance systems, and oxygraphy was found useful in the interpretation of measurements made in patients receiving unknown inspired fractions of oxygen.
Acute oxygen therapy
Oxygen is widely available and commonly prescribed by medical and paramedical staff. When administered correctly it may be life saving, but oxygen is often given without careful evaluation of its
Orthopnea and inspiratory effort in chronic heart failure patients.
CHF patients had a higher diaphragm pressure time product per minute than controls when sitting, and assuming a supine position induced severe dyspnea, a large rise in R,L, and a reduction in C,L so that PTPdi/min increased further.
Increases in intra-abdominal pressure affect pulmonary compliance.
Increased IAP has a major influence on pulmonary compliance (50% decrease at 16 mm Hg) and Measurements of IAP by intraorgan manometry are position dependent and may not accurately reflect the intraperitoneal pressure.
The Washington ManualÒ of Medical Therapeutics
  • 2004
Irwin & Rippe’s Intensive Care Medicine, 5th edn
  • 2003
Respiratory Physiology, 7th edn
  • 2005
Orthopnoea and inspiratory effort in chronic heart failure patients
  • Respiratory Medicine
  • 2003
The ICU Book, 3rd edn
  • 2007