Performance of clinical algorithms for HIV-1 diagnosis and antiretroviral initiation among HIV-1-exposed children aged less than 18 months in Kenya.

@article{Inwani2009PerformanceOC,
  title={Performance of clinical algorithms for HIV-1 diagnosis and antiretroviral initiation among HIV-1-exposed children aged less than 18 months in Kenya.},
  author={Irene Inwani and Dorothy A Mbori-Ngacha and Ruth Nduati and Elizabeth Maleche Obimbo and Dalton C. Wamalwa and Grace John-Stewart and Carey Farquhar},
  journal={Journal of acquired immune deficiency syndromes},
  year={2009},
  volume={50 5},
  pages={
          492-8
        }
}
BACKGROUND Ninety percent of HIV-1-infected children live in sub-Saharan Africa. In the absence of diagnosis and antiretroviral therapy, approximately 50% die before 2 years. METHODS We evaluated sensitivity and specificity of clinical algorithms for diagnosis of HIV-1 infection and antiretroviral therapy initiation among HIV-1-exposed children aged less than 18 months. Children were identified with routine HIV-1 testing and assessed using 3 sets of criteria: (1) Integrated Management of… CONTINUE READING

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