Performance of a second-generation methylated SEPT9 test in detecting colorectal neoplasm.

  title={Performance of a second-generation methylated SEPT9 test in detecting colorectal neoplasm.},
  author={Peng Jin and Qian Kang and Xin Wang and Lang Yang and Yang Yu and Na Li and Yu-qi He and Xiaoliang Han and Jie Hang and Jing Zhang and Lele Song and Ying Han and Jian-qiu Sheng},
  journal={Journal of gastroenterology and hepatology},
  volume={30 5},
BACKGROUND AND AIM Screening and early detection reduces mortality due to colorectal cancer (CRC). Methylated Septin 9 (SEPT9) is a new blood-based biomarker for CRC. We evaluated the performance of the second-generation SEPT9 assay for the detection of colorectal neoplasm, and compared it with fecal immunochemical test (FIT). METHODS A total of 135 patients with CRC, 169 with adenomatous polyps, 81 with hyperplastic polyps, and 91 healthy controls were included. The clinical status of all… CONTINUE READING
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