Performance level modulates adult age differences in brain activation during spatial working memory.

  title={Performance level modulates adult age differences in brain activation during spatial working memory.},
  author={Irene E. Nagel and Claudia Preuschhof and Shu-Chen Li and Lars Nyberg and Lars B{\"a}ckman and Ulman Lindenberger and Hauke R. Heekeren},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={106 52},
Working memory (WM) shows pronounced age-related decline. Functional magnetic resonance imaging (fMRI) studies have revealed age differences in task-related brain activation. Evidence based primarily on episodic memory studies suggests that brain activation patterns can be modulated by task difficulty in both younger and older adults. In most fMRI aging studies on WM, however, performance level has not been considered, so that age differences in activation patterns are confounded with age… CONTINUE READING
87 Citations
53 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 87 extracted citations


Publications referenced by this paper.
Showing 1-10 of 53 references

Age-related decline in brain resources magnifies genetic effects on cognitive functioning

  • U Lindenberger
  • Front Neurosci
  • 2008

Neural correlates of variable working memory load across adult age and skill: Dissociative patterns within the fronto-parietal network

  • L Nyberg, E Dahlin, A Stigsdotter Neely, L Bäckman
  • Scand J Psychol
  • 2008

Varitation in Working Memory (Oxford

  • ARA Conway, C Jarrold, MJ Kane, A Miyake, JN Towse, eds
  • 2008

Impact of complex genetic variation in COMT on human brain function

  • A Meyer-Lindenberg
  • Mol Psychiatry
  • 2006

Similar Papers

Loading similar papers…