Performance evaluation of the new fully automated human immunodeficiency virus antigen-antibody combination assay designed for blood screening.

@article{Sickinger2008PerformanceEO,
  title={Performance evaluation of the new fully automated human immunodeficiency virus antigen-antibody combination assay designed for blood screening.},
  author={Eva Sickinger and Gesa Jonas and Alex W Yem and Andreas Goller and Myriam Stieler and Catherine A. Brennan and Michael Hausmann and G. Schochetman and Sushil G. Devare and Jeffery C. Hunt and H. P. Kapprell and Jane D Bryant},
  journal={Transfusion},
  year={2008},
  volume={48 4},
  pages={584-93}
}
BACKGROUND Before the introduction of human immunodeficiency virus (HIV) combination assays, serologic diagnosis of HIV infection was performed with assays that detected either antibodies or p24 antigen. Owing to the capability to detect the early appearance of p24 antigen, combination assays that are designed for simultaneous detection of antibodies and antigen can significantly reduce the diagnostic window. STUDY DESIGN AND METHODS Specificity and sensitivity of a commercially available HIV… CONTINUE READING

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Before the introduction of human immunodeficiency virus ( HIV ) combination assays , serologic diagnosis of HIV infection was performed with assays that detected either antibodies or p24 antigen .
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