Performance characteristics and clinical utility of a hybrid ELISA for detection of ANA Note

@article{Ulvestad2001PerformanceCA,
  title={Performance characteristics and clinical utility of a hybrid ELISA for detection of ANA Note},
  author={Elling Ulvestad},
  journal={APMIS},
  year={2001},
  volume={109}
}
To investigate the clinical utility of a newly developed hybrid ELISA for antinuclear antibodies (ANA), a cross‐sectional study of patients admitted to the Section of Rheumatology was initiated. The ELISA was compared to indirect immunofluorescence (IIF) on HEp‐2 cells. Accuracy of tests was analyzed using receiver‐operating characteristic methodology (ROC). In addition, diagnostic sensitivity, specificity and predictive values were calculated for each assay. Results from the ROC analysis… 
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