Perfluorooctane sulfonate exposure causes gonadal developmental toxicity in Caenorhabditis elegans through ROS-induced DNA damage.

@article{Guo2016PerfluorooctaneSE,
  title={Perfluorooctane sulfonate exposure causes gonadal developmental toxicity in Caenorhabditis elegans through ROS-induced DNA damage.},
  author={Xiaoying Guo and Qingqing Li and Jue Shi and Liulin Shi and Buqing Li and An Li Xu and Guo-Ping Zhao and Lijun Wu},
  journal={Chemosphere},
  year={2016},
  volume={155},
  pages={115-126}
}
Perfluorooctane sulfonate (PFOS), a common persistent organic pollutant, has been reported to show potential developmental toxicity in many animal studies. However, little was known about its effects on reproductive tissues, especially in the germ line. In the present study, Caenorhabditis elegans was used as an in vivo experimental model to study the developmental toxicity caused by PFOS exposure, especially in the gonads. Our results showed that PFOS exposure significantly retarded gonadal… CONTINUE READING

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