Perfluorochemical rescue after surfactant treatment: effect of perflubron dose and ventilatory frequency.

@article{Wolfson1998PerfluorochemicalRA,
  title={Perfluorochemical rescue after surfactant treatment: effect of perflubron dose and ventilatory frequency.},
  author={Marla R. Wolfson and Nancy E. Kechner and Robert F. Roache and J. P. erre Dechadarevian and Helena E. Friss and S. David Rubenstein and T. H. Shaffer},
  journal={Journal of applied physiology},
  year={1998},
  volume={84 2},
  pages={
          624-40
        }
}
To test the hypotheses that perfluorochemical (PFC) liquid rescue after natural surfactant (SF) treatment would improve pulmonary function and histology and that this profile would be influenced by PFC dose or ventilator strategy, anesthetized preterm lambs (n = 31) with respiratory distress were studied using nonpreoxygenated perflubron. All animals received SF at 1 h and were randomized at 2 h as follows and studied to 4 h postnatal age: 1) conventional mechanical gas ventilation (n = 8), 2… Expand
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Surfactant and partial liquid ventilation via conventional and high-frequency techniques in an animal model of respiratory distress syndrome
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