Percutaneous transluminal coronary angioplasty in evolving acute myocardial infarction.


In 29 patients with evolving acute myocardial infarction, acute reperfusion of the infarct-related coronary artery was attempted using percutaneous transluminal coronary angioplasty (PTCA). Before PTCA, angiography showed 23 totally occluded and 6 severely stenotic infarct-related coronary arteries. PTCA was initially successful in 25 of 29 patients (86%). Reocclusion occurred in 4 patients within 12 hours after successful PTCA and was associated with new electrocardiographic changes or recurrence of symptoms. In 17 patients the infarct-related coronary artery remained patent at early follow-up; late stenosis occurred in 4 patients. Recurrence of stenosis was accompanied by development of angina. No clinical or angiographic features distinguished those with ultimate vessel patency, occlusion or recurrence of stenosis. On follow-up, ventricular function appeared better preserved or improved in those with a patent infarct-related coronary artery than in those with an occluded infarct-related coronary artery. Further studies are warranted to compare PTCA and streptokinase as primary reperfusion modalities in evolving acute myocardial infarction.


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@article{Prida1986PercutaneousTC, title={Percutaneous transluminal coronary angioplasty in evolving acute myocardial infarction.}, author={Xavier E. Prida and Jim P Holland and Robert L. Feldman and James A. Hill and Robert G Macdonald and Charles Richard Conti and Carl J . Pepine}, journal={The American journal of cardiology}, year={1986}, volume={57 13}, pages={1069-74} }