Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 in the canine.

Abstract

Achieving efficient cardiac gene transfer in a large animal model has proven to be technically challenging. Prior strategies have employed cardio-pulmonary bypass or dual catheterization with the aid of vasodilators to deliver vectors, such as adenovirus, adeno-associated virus (AAV) or plasmid DNA. While single-stranded AAV vectors have shown the greatest… (More)
DOI: 10.1007/978-1-61737-982-6_24

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.