Percutaneous radiofrequency ablation for hepatocellular carcinoma

  title={Percutaneous radiofrequency ablation for hepatocellular carcinoma},
  author={Ryosuke Tateishi and Shuichiro Shiina and Takuma Teratani and Shuntaro Obi and Shin'pei Sato and Yukihiro Koike and Tomonori Fujishima and Haruhiko Yoshida and Takao Kawabe and Masao Omata},
Radiofrequency ablation (RFA) was introduced recently as a therapeutic modality for hepatocellular carcinoma (HCC), an alternative to percutaneous ethanol injection therapy (PEIT), which is coming into use worldwide. Previously reported treatment efficacy and complication rates have varied considerably. 
Comparative study of percutaneous radiofrequency ablation and hepatic resection for small, poorly differentiated hepatocellular carcinomas
Evaluated the relative efficacy and safety of hepatic resection or radiofrequency ablation for treating poorly differentiated hepatocellular carcinomas.
Efficacy of additional radiofrequency ablation after transcatheter arterial chemoembolization for intermediate hepatocellular carcinoma
The efficacy of adding radiofrequency ablation to TACE in patients with intermediate HCC was evaluated, and the factors that were associated with favorable survival in these patients were identified.
Percutaneous tumor ablation for hepatocellular carcinoma.
HCC is increasing in incidence and multiple percutaneous ablation methods are now available for primary treatment or for bridging to transplantation.
Comparison of therapeutic effects between radiofrequency ablation and percutaneous microwave coagulation therapy for small hepatocellular carcinomas
This study evaluated the therapeutic efficacy and safety of radiofrequency ablation and percutaneous microwave coagulation therapy for the treatment of small HCC measuring ≤ 2 cm in diameter.
Limitation of repeated radiofrequency ablation in hepatocellular carcinoma: Proposal of a three (times) ×  3 (years) index
This work investigated the controllability of HCC and explored the algorithm of therapeutic strategy for HCC in patients who met the RFA criteria.
Efficacy and safety of radiofrequency ablation for elderly hepatocellular carcinoma patients
This study evaluated the efficacy and safety of radiofrequency ablation (RFA) therapy in elderly patients with hepatocellular carcinoma (HCC) and found it to be safe and effective.
Percutaneous radiofrequency ablation of hepatocellular adenoma: Initial experience in 10 patients
The objective of this study was to assess the therapeutic efficacy and safety of percutaneous radiofrequency ablation for hepatocellular adenoma and to establish a protocol for evaluating the safety and effectiveness of this procedure in patients with liver cancer.
Combined transcatheter arterial chemoembolization and radiofrequency ablation in single‐session for solitary hepatocellular carcinoma larger than 7 cm
To evaluate technical feasibility and treatment results of combined transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) in single‐session for solitary hepatocellular
Radiofrequency ablation for hepatocellular carcinoma: a survival analysis of 117 patients
The objective of this article to report the experience in a tertiary referral hospital of radiofrequency ablation as either first line or in combination with other treatment modality for patients with HCC.


Local recurrence of hepatocellular carcinoma after percutaneous ethanol injection
Percutaneous ethanol injection (PEI) therapy is now widely used for small hepatocellular carcinomas (HCC). However, only limited information is available regarding local tumor recurrence after PEI
Complications of radiofrequency coagulation of liver tumours
The purpose of this study was to assess critically the complication rates of RFC in centres with both large and limited initial experience, and to establish causes and possible means of prevention and treatment.
Hepatocellular carcinoma after transcatheter hepatic arterial embolization. A histopathologic study of 84 resected cases
Transcatheter arterial embolization has been used to treat hepatocellular carcinoma (HCC), yet much is still unknown regarding its optimal use.
Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma
Radiofrequency ablation with cooled‐tip needle for HCC is associated with a high risk of neoplastic seeding, and has to be considered when selecting curative treatments for H CC or adjuvant therapies before liver transplantation.
Radiofrequency Ablation of Hepatocellular Cancer in 110 Patients With Cirrhosis
In patients with cirrhosis and HCC, RFA produces effective local control of disease in a significant proportion of patients and can be performed safely with minimal complications.
Nonsurgical Treatment of Hepatocellular Carcinoma: From Percutaneous Ethanol Injection Therapy and Percutaneous Microwave Coagulation Therapy to Radiofrequency Ablation
By virtue of their local curability, minimal effect on liver function, and easy repeatability for recurrence, image-guided percutaneous tumor ablations, especially RFA, will be increasingly important in the treatment of HCC.
Percutaneous radiofrequency thermal ablation combined with transcatheter arterial embolization in the treatment of large hepatocellular carcinoma.
Percutaneous RF thermal ablation performed after TAE effectively treated HCCs larger than tumors suitable for segmental TAE or RF application alone; the result was achieved in two thirds of the cases in a single session with only one needle electrode insertion.
Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies: results in 123 patients.
RFA is a safe, well-tolerated, and effective treatment to achieve tumor destruction in patients with unresectable hepatic malignancies and multimodality treatment approaches that include RFA should be investigated.
Percutaneous radio-frequency thermal ablation of nonresectable hepatocellular carcinoma after occlusion of tumor blood supply.
Evaluated percutaneous radio-frequency thermal ablation of nonresectable hepatocellular carcinoma (HCC) after occlusion of the tumor arterial supply demonstrated a nonenhancing area corresponding in shape to the previously identified HCC, which was suggestive of complete necrosis.
Small hepatocellular carcinoma: treatment with radio-frequency ablation versus ethanol injection.
RF ablation results in a higher rate of complete necrosis and requires fewer treatment sessions than percutaneous ethanol injection, however, the complication rate is higher with RF ablation than with percutaneously ethanol injection.