Percutaneous penetration/dermal absorption of hair dyes in vitro.

  title={Percutaneous penetration/dermal absorption of hair dyes in vitro.},
  author={Winfried Steiling and J{\"o}rg Kreutz and Harald Hofer},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  volume={15 4-5},
This paper presents an in vitro technique to analyse percutaneous penetration and dermal absorption of hair dyes, topically applied to excised pig skin. Representative examples are given by the radio-labelled hair dyes p-phenylenediamine and bis-(5-amino-1-hydroxyphenyl)-methane. Both compounds were assessed under simulated use conditions and were analysed in representative formulations including the specific conditions for oxidation hair dyes. To be able to differentiate between topically… CONTINUE READING


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