Percutaneous left atrial appendage closure improves left atrial mechanical function through Frank-Starling mechanism.

@article{Coisne2017PercutaneousLA,
  title={Percutaneous left atrial appendage closure improves left atrial mechanical function through Frank-Starling mechanism.},
  author={Augustin Coisne and Rosario Pilato and François Brigadeau and Didier Klug and Christelle Marqui{\'e} and Zouheir Souissi and Marjorie Richardson and St{\'e}phanie Mouton and A S Polge and Patrizio Lancellotti and Dominique Lacroix and David Montaigne},
  journal={Heart rhythm},
  year={2017},
  volume={14 5},
  pages={710-716}
}
BACKGROUND Modifications in left atrial (LA) flow velocities after left atrial appendage (LAA) exclusion have been shown in animal and ex vivo models. In a substudy of PROTECT AF (Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Prevention of Stroke in Patients With Atrial Fibrillation), an objective improvement in quality of life was observed after LAA closure. OBJECTIVE The purpose of this study was to investigate the impact of LAA closure on LA transport… CONTINUE READING
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