Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design.

@article{Lee2015PercutaneousAT,
  title={Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design.},
  author={Randall J. Lee and Dhanunjaya R. Lakkireddy and Suneet Mittal and Christopher Randall Ellis and Jason T Connor and Benjamin R Saville and David J. Wilber},
  journal={American heart journal},
  year={2015},
  volume={170 6},
  pages={
          1184-94
        }
}
BACKGROUND Pulmonary vein antrum isolation (PVI) as a treatment of paroxysmal atrial fibrillation (AF) is associated with a high rate of success; however, outcomes for treating persistent and long-standing persistent AF with PVI alone are substantially lower and often require multiple procedures to maintain long-term freedom from atrial arrhythmias. Foci and/or substrate outside the pulmonary veins, particularly in the left atrial appendage (LAA), has been identified as a key mechanism in the… CONTINUE READING

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