Percutaneous absorption of the sunscreen benzophenone‐3 after repeated whole‐body applications, with and without ultraviolet irradiation

@article{Gonzalez2006PercutaneousAO,
  title={Percutaneous absorption of the sunscreen benzophenone‐3 after repeated whole‐body applications, with and without ultraviolet irradiation},
  author={Helena Gonzalez and Anne Farbrot and Olle Lark{\"o} and Ann-Marie Wennberg},
  journal={British Journal of Dermatology},
  year={2006},
  volume={154}
}
Background  Benzophenone‐3 (BZ‐3; 2‐hydroxy‐4‐methoxybenzophenone, oxybenzone) is commonly used to absorb ultraviolet (UV) radiation. BZ‐3 penetrates the skin and can be found in the urine. The amount varies between 0·4% and 2%. This seems to be the main metabolic pathway in rats. 
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To estimate their reactivity, different prominent UV filter substances are studied, including octocrylene, ethylhexyl salicylate, 4‐t‐butyl‐4′‐methoxydibenzoylmethane, ethYLhexyl methoxycinnamate, benzophenone‐3 and ethyl hexyl triazone.
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