Percutaneous Mitral Valve Repair in the Initial EVEREST Cohort


Left ventricular (LV) remodeling associated with mitral regurgitation (MR) is adaptive in that forward stroke volume (FSV) is preserved, but may eventually become maladaptive, leading to irreversible LV dysfunction and adverse late outcomes even after correction of MR. Several studies have raised the specter of a point of no return, prompting the recommendation for intervention in asymptomatic patients with hemodynamically significant MR when the LV ejection fraction falls below 60% or the LV end-systolic dimension exceeds 40 mm. A concern that surgery itself may contribute to postoperative LV dysfunction has led to modifications of surgical technique, with a strong preference for mitral valve repair over replacement.

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@inproceedings{Foster2013PercutaneousMV, title={Percutaneous Mitral Valve Repair in the Initial EVEREST Cohort}, author={Elyse D Foster and Damon Kwan and Ted Feldman and Jeffrey Weissman and Paul A . Grayburn and Allan Schwartz and Jason H . Rogers and Saibal Kar and Michael J . Rinaldi and Peter S . Fail and James Hermiller and Patrick L . Whitlow and Christopher Herrmann and David Scott Lim and D . Glower}, year={2013} }