Percutaneous MR-guided cryoablation for malignancies, with a focus on renal cell carcinoma

  title={Percutaneous MR-guided cryoablation for malignancies, with a focus on renal cell carcinoma},
  author={Takuji Mogami and Junta Harada and Kouichi Kishimoto and Sajio Sumida},
  journal={International Journal of Clinical Oncology},
Cryosurgery is the oldest thermal ablation method, and was first performed in the mid-nineteenth century. Since the development of cryosurgical systems capable of delivering liquid nitrogen, organs in various regions have been treated with cryosurgery. However, the lack of an adequate monitoring modality during the freezing process did not allow the precise and complete destruction of lesions deep inside the parenchyma. This led to local recurrences caused by unsatisfactory results of treatment… 
Percutaneous Image-guided Thermal Ablation for Renal Cell Carcinoma
This article will review percutaneous image-guided thermal ablation for RCC, covering treatment indications, ablation modalities and techniques, oncologic outcomes, and possible complications.
CT-Guided Percutaneous Cryoablation in Renal Cell Carcinoma: Factors Affecting Local Tumor Control.
Image-guided Cryotherapy for Musculoskeletal Tumors.
Percutaneous cryotherapy can be considered a safe and effective technique in the treatment of benign and malignant musculoskeletal tumors and a valid alternative to radiofrequency ablation.
MR imaging-guided percutaneous cryotherapy for lung tumors: initial experience.
MRI-guided focal therapy in patients with localized (recurrent) prostate cancer
Although comparable results regarding accuracy and speed were found, the extended technical effort of the robotic technique make the manual technique – currently – more suitable to perform MRI-guided biopsies.
Renal cell carcinoma: imaging and therapy
More accurate matching of therapeutic options to newly diagnosed renal carcinomas is now possible with contemporary imaging techniques in order to limit morbidity of surgical treatment.
A Case of Solitary Metastasis from a Hepatocellular Carcinoma to the Sacral Bone Successfully Treated with Percutaneous Cryoablation
A 70-year-old woman, who had previously undergone a hepatectomy for hepatocellular carcinoma (HCC), developed a solitary metastasis in the sacral bone with the symptom of limb pain, believed to be caused by a cryoinjury to the L5 nerve root, which was adjacent to the sacrals tumor.
Factors Affecting Lethal Isotherms During Cryoablation Procedures
Results indicate that selection of the probe manufacturer and probe size may be more important for dictating the size of kill zones during cryoablation than procedural adjustments to operating pressures or freeze times.
MRI-guided interventions for the treatment of prostate cancer.
MRI-guided laser ablation and MRI-guided focused ultrasound are the most promising options for focal treatment of the prostate in patients with prostate cancer.


Initial experience of percutaneous renal cryosurgery under the guidance of a horizontal open MRI system.
In this limited clinical trial of percutaneous renal tumor surgery, cryoablation demonstrated its feasibility with minimal morbidity, and intraprocedual MR-guided cryosurgery can be used as a safe modality, although further studies are necessary to determine the long-term efficacy of this procedure.
Percutaneous cryosurgery for renal tumours.
Percutaneous cryosurgery was performed successfully in two patients with hypervascular renal tumours and the whole kidney, including the tumour, became necrotic and shrunken post-operatively, suggesting that percutaneous Cryo-immunological activity was assumed to have contributed to the temporary improvement in their condition.
MR imaging-guided percutaneous cryotherapy of liver tumors: initial experience.
MR imaging-guided percutaneous cryotherapy of liver tumors is feasible and safe and MR imaging can be used to estimate cryotherapy effects and guide therapy intraprocedurally.
Laparoscopic renal cryoablation in 32 patients.
[Sequential MRI and CT monitoring in cryosurgery--an experimental study in rats].
  • H. Isoda
  • Medicine
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica
  • 1989
Investigating whether the image diagnosis such as Magnetic Resonance (MR) and CT is useful for the determination of the region during and after cryosurgery concluded that MRI and CT are useful for monitoring the process of cryOSurgery during and immediately after the procedure.
Application of cryogenic surgery to resection of parenchymal organs.
This cryosurgical system can provide a safe, controllable method of necrosis of biologic tissue in situ as well as a relatively avascular means of surgical removal of neoplasms.
Real-time I-MR-imaging--guided cryoablation of uterine fibroids.