Percutaneous Absorption of Mexoryl SX® in Human Volunteers: Comparison with in vitro Data

@article{BenechKieffer2003PercutaneousAO,
  title={Percutaneous Absorption of Mexoryl SX® in Human Volunteers: Comparison with in vitro Data},
  author={F. Benech-Kieffer and W. Meuling and C. Leclerc and L. Roza and J. Leclaire and G. Nohynek},
  journal={Skin Pharmacology and Physiology},
  year={2003},
  volume={16},
  pages={343 - 355}
}
The potential human health risk of UV filters depends on their toxicity and the human systemic exposure which is a function of the extent of percutaneous absorption of the topically applied substance into the human organism. Using a ‘mass balance’ approach, a study was designed to investigate the systemically absorbed dose of [14C]-Mexoryl SX® in humans after topical application of a typical sunscreen emulsion. In addition, to assess the correlation with in vitro experiments, the percutaneous… Expand
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