Perceptual-motor skill learning in Gilles de la Tourette syndrome Evidence for multiple procedural learning and memory systems

@article{Marsh2005PerceptualmotorSL,
  title={Perceptual-motor skill learning in Gilles de la Tourette syndrome Evidence for multiple procedural learning and memory systems},
  author={Rachel Marsh and Gerianne M. Alexander and Mark G. Packard and Hongtu Zhu and Bradley S. Peterson},
  journal={Neuropsychologia},
  year={2005},
  volume={43},
  pages={1456-1465}
}

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The authors examined motor (Serial Reaction Time task, SRT) and cognitive (Probabilistic Classification task, PCT) skill learning in patients with schizophrenia and normal controls and found dysfunction in a specific corticostriatal subcircuit.

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The hypothesis that overactive dopamine transmission leads to excessive reinforcement of motor sequences, which might explain the formation of tics in Gilles de la Tourette syndrome is supported.

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A Process-Oriented View of Procedural Memory Can Help Better Understand Tourette’s Syndrome

Tourette’s syndrome (TS) is a neurodevelopmental disorder characterized by repetitive movements and vocalizations, also known as tics. The phenomenology of tics and the underlying neurobiology of the

Annual research review: The neurobehavioral development of multiple memory systems--implications for childhood and adolescent psychiatric disorders.

Considering Tourette syndrome, attention-deficit/hyperactivity disorder, obsessive-compulsive disorder, eating disorders, and autism spectrum disorders within the context of multiple memory systems may help elucidate the pathogenesis of habit-like symptoms in childhood and adolescence, and lead to novel treatments that lessen the habits of these disorders.

Procedural learning: A developmental study of motor sequence learning and probabilistic classification learning in school-aged children

The hypothesis of age invariance from motor to cognitive procedural learning, which had not been done previously, was extended and the ability to adopt more efficient learning strategies with age may rely on the maturation of the fronto-striatal loops.

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