Perception of UV-B by the Arabidopsis UVR8 Protein

  title={Perception of UV-B by the Arabidopsis UVR8 Protein},
  author={Luca Rizzini and Jean-Jacques Favory and Catherine Cloix and Davide Faggionato and Andrew O'Hara and Eirini Kaiserli and Ralf Baumeister and Eberhard Schäfer and Ferenc Nagy and Gareth I. Jenkins and Roman Ulm},
  pages={103 - 106}
A plant ultraviolet-B photoreceptor uses a tryptophan-based chromophore. To optimize their growth and survival, plants perceive and respond to ultraviolet-B (UV-B) radiation. However, neither the molecular identity of the UV-B photoreceptor nor the photoperception mechanism is known. Here we show that dimers of the UVR8 protein perceive UV-B, probably by a tryptophan-based mechanism. Absorption of UV-B induces instant monomerization of the photoreceptor and interaction with COP1, the central… 

The UV-B Photoreceptor UVR8: From Structure to Physiology

Low doses of UV-B light (280 to 315 nm) elicit photomorphogenic responses in plants that modify biochemical composition, photosynthetic competence, morphogenesis, and defense and much remains to be learned about the physiological role of UVR8 and its interaction with other signaling pathways, the molecular mechanism of U VR8 photoreception, how the UVR7 protein initiates signaling, how it is regulated, and how UVR9 regulates transcription of its target genes.

Dual-Source Nuclear Monomers of UV-B Light Receptor Direct Photomorphogenesis in Arabidopsis.

How plants cope with UV-B: from perception to response.

Arabidopsis UV-B Photoreceptor and Its Light Signal Transduction in Plants: Arabidopsis UV-B Photoreceptor and Its Light Signal Transduction in Plants

The Arabidopsis thaliana protein UVR8 is a photoreceptor for ultraviolet-B, mediating UV-B-induced photomorphogenesis. Under light conditions devoid of UV-B, UVR8 is localized in both the cytoplasm

UV-B photoreceptor-mediated signalling in plants.

How Does Photoreceptor UVR8 Perceive a UV‐B Signal?

Recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV‐B perception at the molecular level are summarized.

The UVR 8 UV-B Photoreceptor : Perception , Signaling and Response TILBROOK , Kimberley

The biological process in plants from initialUV-B perception and signal transduction through to the known UV-B responses that promote survival in sunlight is reviewed.

The UVR8 UV-B Photoreceptor: Perception, Signaling and Response

UVR8 UV-B signaling represents the further understanding of how plants are able to sense their light environment and adjust their growth accordingly and is reviewed.

Structure and function of the UV-B photoreceptor UVR8.

  • G. Jenkins
  • Biology
    Current opinion in structural biology
  • 2014

Reversion of the Arabidopsis UV-B photoreceptor UVR8 to the homodimeric ground state

  • M. HeijdeR. Ulm
  • Biology
    Proceedings of the National Academy of Sciences
  • 2012
It is shown that UVR8 monomerization is reversible in vivo, restoring the homodimeric ground state and identifies a key role of RUP1- and RUP2-mediated U VR8 redimerization in photoreceptor inactivation, a crucial process that regenerates reactivatable UVR7 homodimers.



A UV-B-specific signaling component orchestrates plant UV protection.

  • B. A. BrownC. Cloix G. Jenkins
  • Environmental Science, Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2005
It is reported that Arabidopsis UV RESISTANCE LOCUS 8 (UVR8) is a UV-B-specific signaling component that orchestrates expression of a range of genes with vital UV-protective functions and it is demonstrated that HY5 is a key effector of the UVR8 pathway, and that it is required for survival underUV-B radiation.

Signalling and gene regulation in response to ultraviolet light.

Arabidopsis UVR8 Regulates Ultraviolet-B Signal Transduction and Tolerance and Contains Sequence Similarity to Human Regulator of Chromatin Condensation 1

Results suggest that UVR8acts in a UV-B signal transduction pathway leading to induction of flavonoid biosynthesis, an indication of increasedUV-B injury.

Signal transduction in responses to UV-B radiation.

  • G. Jenkins
  • Environmental Science
    Annual review of plant biology
  • 2009
Photomorphogenic signaling stimulates the expression of genes involved in UV-protection and hence promotes plant survival inUV-B, and is mediated by the UV-B-specific component UV RESISTANCE LOCUS8 (UVR8).

UVR8 in Arabidopsis thaliana regulates multiple aspects of cellular differentiation during leaf development in response to ultraviolet B radiation.

The findings show that, in addition to regulating UV-protective gene expression responses, UVR8 is involved in controlling aspects of leaf growth and morphogenesis, extending the understanding of how UV-B response is orchestrated at the whole-plant level.

Role of root UV-B sensing in Arabidopsis early seedling development

The identification of an Arabidopsis mutant, root UVB sensitive 1 (rus1), whose primary root is hypersensitive to very low-fluence-rate (VLF) UVB, demonstrates a root VLF UVB-sensing mechanism that is involved inArabidopsis early seedling morphogenesis and development.

Interaction of COP1 and UVR8 regulates UV‐B‐induced photomorphogenesis and stress acclimation in Arabidopsis

It is suggested that UV‐B‐specific interaction of COP1 and UVR8 in the nucleus is a very early step in signalling and responsible for the plant's coordinated response toUV‐B ensuring UV‐ B acclimation and protection in the natural environment.

CONSTITUTIVELY PHOTOMORPHOGENIC1 Is Required for the UV-B Response in Arabidopsis[W]

It is concluded that COP1 performs a specific and novel role in the plants' photomorphogenic response to UV-B, coordinating HY5-dependent and -independent pathways, which eventually results inUV-B tolerance.

Light-regulated plant growth and development.

UV-B Promotes Rapid Nuclear Translocation of the Arabidopsis UV-B–Specific Signaling Component UVR8 and Activates Its Function in the Nucleus

It is shown that UV-B stimulates the nuclear accumulation of both a green fluorescent protein (GFP)-UVR8 fusion and native UVR8, indicating a concerted mechanism for nuclear translocation.