Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival.

@article{Bomken2011PercentageTN,
  title={Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival.},
  author={Simon Bomken and Beverley A Davies and Leeai Chong and Michael Cole and Katrina M. Wood and Michael McDermott and Deborah Anne Tweddle},
  journal={Pediatric hematology and oncology},
  year={2011},
  volume={28 2},
  pages={106-14}
}
The percentage of chemotherapy-induced necrosis in primary tumors corresponds with outcome in several childhood malignancies, including high-risk metastatic diseases. In this retrospective pilot study, the authors assessed the importance of postchemotherapy necrosis in high-risk neuroblastoma with a histological and case notes review of surgically resected specimens. The authors reviewed all available histology of 31 high-risk neuroblastoma cases treated with COJEC (dose intensive etoposide and… CONTINUE READING

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High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2010
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