Perceived treatment, feedback, and placebo effects in double-blind RCTs: an experimental analysis

@article{Colagiuri2009PerceivedTF,
  title={Perceived treatment, feedback, and placebo effects in double-blind RCTs: an experimental analysis},
  author={Ben Colagiuri and Robert A. Boakes},
  journal={Psychopharmacology},
  year={2009},
  volume={208},
  pages={433-441}
}
In double-blind randomized placebo-controlled trials (RCT) of therapeutic interventions, the effects of the treatment may provide feedback that undermines blinding and consequently distorts measures of the effectiveness of the intervention. This possibility was confirmed in an experimental model using a dummy placebo procedure whereby participants were led… CONTINUE READING