Perampanel in patients with refractory and super-refractory status epilepticus in a neurological intensive care unit

@article{Rohracher2015PerampanelIP,
  title={Perampanel in patients with refractory and super-refractory status epilepticus in a neurological intensive care unit},
  author={Alexandra Rohracher and Julia H{\"o}fler and Gudrun Kalss and Markus Leitinger and Georgi Kuchukhidze and I. De{\'a}k and Judith Dobesberger and Helena Molnar Novak and G{\"u}nter Pilz and Alexander Zerbs and Eugen Trinka},
  journal={Epilepsy & Behavior},
  year={2015},
  volume={49},
  pages={354-358}
}
INTRODUCTION In refractory status epilepticus (SE), because of subcellular maladaptive changes, GABAergic drugs are no longer effective, and the excitatory neurotransmitter glutamate (Glu) plays a major role in seizure perpetuation. Perampanel (PER, licensed since 09/2012) is the first orally active noncompetitive AMPA receptor antagonist for adjunctive treatment of refractory focal epilepsy. METHODS We analyzed treatment response, seizure outcome, and adverse effects of add-on treatment with… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

Perampanel — effective and safe via percutaneous gastric tube in HIV epileptic patient with concomitant highly active antiretroviral therapy

G Caravias, M Geit, M Vosko, G. Ransmayr
  • Epilepsia, Supp
  • 2014
VIEW 1 EXCERPT

Possible effect of perampanel on focal status epilepticus after generalized tonic–clonic status epilepticus

J Rösche, C Kampf, R. Benecke
  • Acta Neurol Belg
  • 2014
VIEW 2 EXCERPTS

Gastrointestinal dysmotility: evidence and clinical management.

  • Current opinion in clinical nutrition and metabolic care
  • 2013
VIEW 1 EXCERPT

Perampanel in posthypoxic myoclonus. Poster presented at "The 4th London-Innsbruck Colloquium on status epilepticus and acute seizures" Salzburg, Austria, April 4th-6th

G. Caravias
  • Epilepsia,
  • 2013
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…